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Cancer

RFQMR technology has a totally different approach from conventional therapies such as chemotherapy, radiotherapy or surgery.This safe treatment alternative may control the tumor growth process through its effect in the cell division mechanism. It can stop tumor activity and growth and provide relief to symptoms such as pain, lack of appetite and weight loss.

The Cytotron is having significant impact in the treatment of cancer and osteoarthritis in Asia & Europe, as evidenced by some recently concluded clinical studies. In cancer, an all comer, compassionate Phase I clinical trial was conducted in Bangalore, India, to treat terminally ill cancer patients with metastatic /end-stage disease, as well as degenerative diseases such as osteoarthritis.  RFQMR is a safe, affordable and effective treatment alternative that uses very low frequency, non-ionizing, non thermal electromagnetic waves in the radio or sub-radio frequencies. In cancer, these waves are hypothetically believed to trigger programmed cell death and stop tumor growth through its effects on cell division. It is crucial to leverage the prevailing state of the art genome-wide or pathway specific molecular technologies (mutational analysis, gene expression profiling and biomarker identification) to study the near and long term effects and the mechanism of action of RFQMR in human tissues. This can be enabled using in-vitro, in-vivo and ex-vivo systems of tumor stem cells, multiple cell types, cell lines, tissue and organ explants, human tumor xenografts, and other animal model systems of disease. Parallel clinical studies need to be conducted to expand the application of RFQMR to primary cancer and other disease indications like pain management, macular degeneration, tissue regeneration and wound healing, to name a few.. There is on-going R&D for other indications such as multiple sclerosis, macular degeneration, diabetic neuropathy & targeted drug delivery, to name a few.

Focused Resonance Nanopermeabilization or FORN, could be defined as combined antitumor treatment that consists of systemic or local administration of cytotoxic drug (e.g. chemotherapy) followed by focused resonance radio frequency pulses delivered to the tumor or the whole body using specially designed delivery system. All cells and tissue, cancer or otherwise have a specific resonance frequency dependant on the density or concentration of hydrogen atoms in a group of these (similar) cells. When these cells are placed in a high instantaneous magnetic field, the protons in them get oriented. At this moment if a radio frequency pulse close to the resonating frequency of the cell colony is fired, these cells start attaining the beat frequency. As the frequency gets closer and closer to the resonating frequency, the resultant frequency remains constant but and the amplitude starts rising, thus increasing the trans membrane potentials many times causing temporary pathways which would close when the signal is removed after the drug passes through the cell membrane. The interesting and unique fact of this technique is that cell permeabilization occurs only in those cells or tissues (group of cells) that are in resonance and attain beat frequency. The non-resonating cells do not respond to the FORN treatment, as they are in their resting state. Consequently the main factors that play crucial role in obtaining high responses of the FORN treatment are the drug used in the treatment and the technique and method of creating controlled resonance, and beating it accurately so as to increase the membrane potential to a specific value and for a predetermined time interval sufficient to transport the interested molecule through the temporary pathway and deliver to the tumor.

(WO/2010/106544) A METHOD AND APPARATUS FOR - FOCUSED RESONANCE NANOPERMEABILIZATION (FORN)

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